Melkin is a graduate of the London International School of Performing Arts (LISPA). Since 2007, he has been an actor and director at Liquid Theater. He is a laureate of the National Theater Award "Golden Mask" in the "Experiment" category. Since 2011, he has led the LOW TECH studio and is a resident of the Meyerhold Center. Melkin has created productions such as Solaris, Palms, In Praise of Idleness, and others. He studied biomechanics under Alexey Levinsky. As a director and educator, he taught at the Moscow Art Theatre School in Dmitry Brusnikin's workshop. His production of The Forest received numerous positive reviews from critics and earned five stars at the Edinburgh Fringe Festival.